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Low Dose Naltrexone for Weight Loss: New Way To Reach Your Goals

Low Dose Naltrexone for weight loss
Woman checking her waist length

Low dose naltrexone (LDN) for weight loss is a relatively new supplement that is coming to recognition now. Discover whether this versatile medication could be the key to reaching your ideal weight.


Low dose naltrexone (LDN), a medication initially developed to treat addiction, has recently gained attention for its potential role in weight loss. In this blog post, we’ll explore the current research on LDN and weight loss, discuss how it may work, and determine if it could be a viable option for those looking to shed extra pounds.

What is Low Dose Naltrexone (LDN)?

Naltrexone is a medication traditionally prescribed in higher doses to treat alcohol and opioid dependence. However, when administered in smaller doses (typically 1.5-4.5 mg per day), it exhibits a unique set of properties that can benefit various health conditions. This low-dose version is what we refer to as Low Dose Naltrexone or LDN.

Low Dose Naltrexone and Weight Loss: The Research

While research on LDN for weight loss is still in its infancy, some studies suggest that it could help individuals achieve and maintain their weight loss goals:

  1. Appetite Suppression

LDN may help suppress appetite by interacting with the brain’s opioid receptors, which play a role in regulating hunger and satiety. By blocking these receptors, LDN could potentially reduce food cravings and promote weight loss.

2. Enhanced Metabolism

Preliminary research suggests that LDN may boost metabolism by increasing the body’s production of growth hormone. This effect could lead to increased calorie burning and weight loss over time.

3. Reduced Inflammation

Chronic inflammation is associated with obesity and various health conditions. LDN has been shown to reduce inflammation, which could potentially contribute to weight loss by improving overall metabolic health.

4. Improved Insulin Sensitivity

LDN may improve insulin sensitivity, helping the body use glucose more efficiently and reducing the risk of weight gain associated with insulin resistance.

It’s important to note that research on LDN and weight loss is still limited, and more extensive studies are needed to fully understand its potential in this area.

Is Low Dose Naltrexone Right for Your Weight Loss Journey?

Given the limited research on LDN and weight loss, it’s essential to approach this treatment with caution. While some individuals may experience weight loss benefits, others may not see the same results. Furthermore, LDN should not be considered a stand-alone solution for weight loss but rather as a potential complementary therapy alongside a healthy diet and regular exercise.

Before considering LDN as a weight loss aid, consult with a knowledgeable healthcare professional to assess its suitability for your specific needs and ensure its safe and effective use.


Low dose naltrexone is a versatile medication with a growing body of research supporting its potential role in weight loss. Although current evidence is limited, LDN may offer appetite suppression, enhanced metabolism, and improved insulin sensitivity for some individuals. As with any weight loss intervention, it’s crucial to consult with a healthcare professional before embarking on LDN therapy to ensure its safety and effectiveness for your unique circumstances.

Keep in mind that sustainable weight loss is best achieved through a combination of healthy eating, regular exercise, and, when necessary, the guidance of your physician. Balancing hormones is one of the most important aspect of helping you sustain a healthy weight.

Please click here to see how Acupuncture can help your weight loss journey.

Peptide therapy is another much discussed method of losing weight where appropriate.

To learn more about combining Ozempic with several other modalities, please click here.

If you or someone you love is struggling to lose weight, please contact Dr. Kumar at (561) 210-9999 for a thorough evaluation and recommendations to help you achieve a healthy weight that is sustainable over the long term. We look forward to helping you reach your goals!


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